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Audrey FERRAND

TOULOUSE

En résumé

Education:
09/01/2006-31/01/2009
Medical scientist, Instructor
University of Melbourne
Heidelberg, VIC, Australia

01/31/2005-07/31/2006
Post-doctoral training: Research Fellow in Cancer Research
Harvard Medical Shool
Boston, MA, USA

09/01/2000-11/05/2004
PhD in Molecular and Cellular Biology and Pharmacology
INSERM U.531, Toulouse, France
PhD obtained on November 2004
Manuscript title: Gastrin peptides signaling: involvement in pancreas and colon cancers
Paul Sabatier University, Toulouse, France.

09/01/1998-07/18/2000
Master in Molecular and Cellular Biology and Pharmacology
(Diplome d’Etudes Approfondies)
with honors (rank: 2/17)
INSERM U.531, Toulouse, France
Paul Sabatier University, Toulouse, France.

09/01/1995-07/15/1998
Bachelor degree in Molecular and Cellular Biology, Physiology and
Immunology (“DEUG” and “Licence”)
Paul Sabatier University, Toulouse, France.

09/01/1993-07/15/1995
First university degree of medical school (No validated)
Paul Sabatier University, France.

07/05/1993 High School Diploma (“baccalauréat”) in Sciences and Biology
with honors
Lycée polyvalent, Villefranche de Rouergue, France.


Editorial Boards:

2003-Present: Ad-hoc reviewer for the American Journal of Physiology
Since 2005: Ad-hoc reviewer for Cancer Letters
Ad-hoc reviewer for Oncogene
Ad-hoc reviewer for Genetics
Ad-hoc reviewer for the Journal of the National Cancer Institute

Awards and Honors:

2006: Young researcher award
from The French National Academy of Science

10/01/2003-10/01/2004: Fellowship for 1 year PhD program
from National Ligue against Cancer

03/26/2004: Young researcher award
from the French National Society of Gastroenterology

10/01/2000-10/01/2003: Fellowship for 3 years PhD program
from the Education and Research Department of the French government

01/23/2003: Young researcher award
from the European Club of Digestive Epithelial Cells

04/13/2002: Travel grant during the PhD training
from the scientific committee of the Paul Sabatier Universtity
(Collaboration between the INSERM U.531, Toulouse, France and the Gastroenterology department, University of Massachusetts Medical School, Worcester, MA, USA.)

08/29/2002: Travel grant
from the steering committee of the 14th Regulatory Peptides Meeting



Report of Teaching

02/01/2004-02/28/2004:
Lecturer in Pharmacology (Master degree)
Paul Sabatier University, Toulouse, France.

08/01/2003-09/30/2003:
Research trainer for undergraduate student during his master degree.

02/01/2003-02/28/2003:
Lecturer in Molecular and Cellular Physiopathology (Pre-Doctoral
degree)
Paul Sabatier University, Toulouse, France.

10/01/2000-10/01/2003:
Lecturer in Pharmacology (Master degree)
Lecturer in Endocrinology (Pre-Master degree)
Lecturer in Cellular Biology and Animal Physiology (Bachelor degree)
Paul Sabatier University, Toulouse, France.

Mes compétences :
Encadrement
Enseignement
Management
Monitorat
Pharmacologie
Pharmacology
Signalisation cellulaire
Stem Cells
Teaching

Entreprises

  • Institut de Recherche en Sant Digestive, INSERM u1220 - CR1 INSERM - Group Leader

    2016 - maintenant https://www.irsd.fr/audrey-ferrand.html

    My research interest is on the Interrelationship between epithelial cells and their environment in colorectal diseases.
    ​Colorectal epithelial cells constantly interact with their microenvironment, particularly with the fibroblasts which represent the major cell population within the stroma. Under physiological condition or during inflammatory bowel diseases or cancer, these interactions between the epithelium and the stroma regulate the phenotypes and behaviour of the cells in these tissues. For example, fibroblasts surrounding colorectal crypt actively participate to the colorectal stem cell niche by regulating their proliferation, differentiation but also the migration process involved in the renewal of the colorectal epithelium. Under tumoral or inflammatory conditions, these interactions are altered which contributes to the disease development, including the metastasis process in cancer.
    By combining morphological, functional, pharmacological and microfluidic approaches to 3D cell primocultures of colorectal organoids and fibroblasts, coupled to orthotopic grafting on murine models, we study the interactions between normal or cancer stem cells and fibroblasts in the various stages of colorectal tumorigenesis
  • Centre de Recherche en Cancérologie de Toulouse - CR1 INSERM

    2011 - 2015
  • University of Melbourne - Medical scientist

    2006 - 2009 Depuis Octobre 2006, je travaille dans le "Regulatory peptide group" du departement de Chirurgie de L'Universite de Melbourne.
    Dans la continuite de ma these, nous etudions le role des peptides gastriniques dans les cancers coliques ainsi que l'implication du metabolisme ferrique dans la regulation de leur activite biologique dans cette pathologie.
    En tant que Staff du departement, je participe a la formation et l'evaluation des etudiants.
  • MGH Cancer center - Research fellow / Post-doc

    2005 - 2006 De février 2005 a Aout 2006, j'ai effectué un stage post-doctoral au MGH Cancer center où je travaillais sur l'identification de nouvelles cibles thérapeutiques dans ces cancers. Dans le cadre de ce projet, j'étais membre du groupe de "Thérapeutique moléculaire des cancers" du MGH cancer center. J'avais également le statut d'"Officer" de la Harvard Medical School. Je suis co-auteur d'une publication dans PNAS et d'une dans Cancer Research.
  • INSERM - PhD student

    PARIS 13 2000 - 2004 J'ai obtenu ma thèse en Innovation Pharmacologique en novembre 2004 à L'université Paul Sabatier de Toulouse. Le titre de mon manuscrit est: "Signalisation des peptides gastriniques: implication dans les cancers pancréatique et colique".
    J'ai réalisé ma thèse en 4 ans, d'une part dans un laboratoire INSERM sur Toulouse, d'autre part dans un laboratoire de l'école de médecine de l'Université du Massachusetts. Mes travaux de thèse ont donné lieu à 5 publications en tant que premier auteur (Exp Cell Research 2004, JBC 2005, Cancer Research 2005, World J Gastroenerology 2006a et 2006b in press), et 6 publications en tant que co-auteur.
  • Université Paul Sabatier - Lecturer in Pharmacology, Cell Biology and Physiology

    Toulouse 2000 - 2004 Dans le cadre du Monitorat, j'ai effectué 296h d'enseignement en DEUG, Licence et Maîtrise réparties entre des travaux dirigés, des travaux pratiques mais aussi en cours magistraux (Pharmacologie et Endocrinologie).
    J'ai également eu la responsabilité d'un atelier portant sur l'implication des RCPG dans les cancers, dasnle cadre du Master de Physiopathologie Moléculaire, cellulaire et intégrée (Toulouse III).

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