Nicolas Fazilleau

- Present experience:
McHeyzer-Williams Lab, The Scripps Research Institute, San Diego, CA, USA.

The ultimate goal of a vaccine is to develop long-lived immunological protection.
Insights into the complex cellular processes of memory development may reveal new treatment modalities for a broad range of clinically-relevant conditions such as autoimmune disease, cancer, transplant rejection, the management of various infectious diseases and allergic responses.
Our long-term goal is to unravel the mechanisms controlling immune memory. My main project is focused on the hypothesis that antigen-specific T cell memory is organized into multiple compartments each sub-specialized in function. I am currently determining the extent of memory T cell function at the peak of the antigen-specific memory response in vivo and defining the capacity of these memory T cell subsets to regulate antigen-specific memory B cell responses in vivo.

- Past research experience:
+ Pasteur Institute, Paris, France, Unit INSERM U277 directed by P. Kourilsky, PhD studies under the supervision of J. Kanellopoulos.
Basic Research on diversity of antigen receptors of T lymphocytes

+ Karolinska Institute, Stockholm, Sweden, Training course under the supervision of E. Linder.
Basic Research on schistiosomasis

- Hobbies
Sports
Travel
Paris