Dominique BonafouxSenior Scientist, Abbott LaboratoriesCambridge - Etats-Unis |
Since 2006: Senior Scientist |
- Project leader (R&D medicinal chemistry) - Manager of multidisciplinary teams - Member of the comity in charge of evaluating new therapeutic targets to maintain a strong R&D pipeline |
2005 - 2006 : Scientist II – Medicinal Chemistry |
- Evaluation the drugability of cytokine related projects in early discovery. - Responsible for the discovery of novel inhibitors of TGF-b receptor 1, with improved pharmacokinetic profiles, for the treatment of fibrosis. - Manager of a research associate. ... |
2001 - 2005 : Principal Scientist – Discovery Medicinal Chemistry |
- Design and synthesis of new drug candidates for the treatment of inflammatory disorders and hypertension. Optimization of their PK/ADME properties. - Responsible for reviewing and assessing the metabolic stability/liability and potential toxicity of ... |
Former student of |
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