I belong at present in fixed term contract in the pharmaceutical group Hoffmann-La Roche in Basel (Switzerland). I'm working in the Chemical proteomic unit where we are using specificity kinase inhibitor columns to evaluate binding properties of kinase inhibitors in cell line or tissue extracts
I am looking for a permanent position in the pharmaceutical domain in Basel or around. My qualifications allow me to aspire as well to a post of Scientific Assistant in R&D as a post in project or quality management and marketing
You can directly contact me : aurelie.w@voila.fr
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Aurélie WINTERHALTER
Research Ingineer - Hoffmann - La Roche (Basel)
Rixheim - France
| English | French |
Schools attended |
Université Montpellier 1 (IUP - Ingénierie Santé) |
Université Lille 1 Sciences et Technologies (IUP Génomique et Protéomique) |
Université Lille 1 Sciences et Technologies (Deug Sciences de la Vie) |
Since 2008: Hoffmann La Roche (Basel) |
Employee
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Employee in the Research Department of Molecular Medicine Laboratories, more particularly in the unit of Chemical Proteomics (Dr A. Augustin). Revealing of protein interactions realized by diverse pharmaceutical drugs to study their secondary effects. Cell culture, Affinity chromatography, LC-MS | |
Sector: Pharmaceutical |
Since 2007: Hoffmann - La Roche (Basel) |
Employee
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Employee for 9 month in the Research Department of Metabolic and vascular diseases, more particularly in the unit of development and in vitro pharmacology (Dr Marc Bedoucha). Creation of differents transgenic cells. Investigation of differents cell receptors and transporters. Cell culture, gene cloning and expression on differents cells lines (eukaryotes, prokaryotes), vector designing, mutagenesis, PCR, sequencing, Western Blot, FRET, use of FLEX and FLIPR stations, smattering on FACS. | |
Sector: Pharmaceutical |
2007 : Hoffmann - La Roche (Basel) |
Trainee
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6 month Trainee in the Neurology Research department in the unit of Alzheimer disease (Dr Céline ADESSI). Revealing of the beta amyloid peptide digestion by the Insulin degrading Enzyme (IDE) in vitro and in cellulo. Cell culture and cloning, preparation of cell extracts, analysis of the kinetic of digestion and tests of synthetic compounds activating IDE. Use of ELISA, LP-ECL technology (Bioveris) and fluorescent quenching assay. | |
Sector: Pharmaceutical |
2006 : Research department of ESBS (Biotechnology school) in Strasbourg |
Trainee
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6 month Trainee in the research laboratory of genome integrity (Dr Jérôme Wagner). Investigation of the human DNA-polymerase kappa in the translesional replication. Gene cloning, expression in bacteria, diverse chromatography purifications and analysis of its replicative properties. | |
Sector: Research and development |
2004 : Research department in the "Kantonspital" in Basel |
Trainee
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Trainee in the Cardiobiology Research Laboratory. Investigation of apoptosis moleculars targets in cardiacs cells. Cell culture, RNA and proteins extraction and purification, immunofluorescence and immunohistochemy. | |
Sector: Research and development |
2003 : Biology Institute in Lille |
Trainee
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Trainee in the research Laboratory of Genetics for multifactors diseases. Research of genetics polymorphisms of Obesity and Diabetes. Screening and genotyping with PCR, sequencing and haplotypes studies with cass/witness comparison. | |
Sector: Research and development |
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Interests |
Skiing, running Evening out with friends (Cinema, Concerts) Traveling Cooking Decoration Architecture |